The concept of flexible radio plays a central role in future mobile communication systems. It will enable to dynamically reconfigure on a software basis wireless systems while at the same time making an optimum use of the different heterogeneous standards (for example WiMAX and 3G LTE) within the same device (base station for example). The scientific challenges are important and touch upon every layer of the telecommunication stack. It is in order to develop tomorrow's innovative wireless systems, adapted to dynamic and heterogeneous environments, that Alcatel-Lucent and Supelec have established this teaching and research chair.